I've summarized the fatal reason why I lose money with my on-chain meme into seven words: "Don't sell when you're making money, sell when you're losing money." The stocks I buy are likely to start with a profit, but in the end, those with poor judgment lose ten times their initial investment without even breaking even. If I don't lose money, who will? And these stocks are simply not suitable for "diamond hands" (i.e., investment decisions based on poor judgment will lead to permanent losses.)