Analysis of the BIO Protocol Upbit Listing: Clarification of Timeline and DeSci Sector Outlook
Key findings
Important clarification : The BIO protocol did not receive spot trading support on Upbit in January 2025. Research indicates that BIO's actual Upbit listing date was October 20, 2025 , supporting KRW, BTC, and USDT trading pairs. In January 2025, BIO was only listed on exchanges such as Binance, Bitget, and Gate.io.
DeSci sector performance analysis in January 2025
Overall trend of the sector
In January 2025, the DeSci sector did show a strong bull market trend , with the following key indicators:
| index | Performance | Driving factors |
|---|---|---|
| Average increase | +11.55% | New project listing boom |
| Sector market capitalization | ~ $900M (January 21st) | BIO and other major projects join |
| Market sentiment | Highly bullish | Endorsement by KOLs such as Vitalik |
| Number of new projects | 30+ | Capital inflow and ecological expansion |
Performance of major DeSci projects in January
| project | Market capitalization | January performance | Key Events |
|---|---|---|---|
| BIO Protocol | $324M | ATH $0.92 → $0.25 (-73%) | Binance listing on January 3 |
| OriginTrail (TRAC) | $350M+ | Estimated +5-15% | Leader in Data Integrity |
| VitaDAO (VITA) | ~$50M | Rising in tandem with the sector | Pioneer in longevity research |
| ResearchCoin (RSC) | Peak $200M | ATH $1.51→$0.61 (-60%) | Record high on January 5 |
Historical Analysis of Upbit's Listing Effect
Typical manifestation patterns
Based on historical data from 2024-2025, Upbit listings generally follow the following pattern:
| stage | Timeframe | Price performance | Success rate |
|---|---|---|---|
| Initial outbreak | Listing day | +50-150% | 70-80% |
| Peak hold | 1-3 days | Volatility Consolidation | 37% |
| Callback phase | 1-4 weeks | -50-70% | 89% |
| Long-term performance | 3-6 months | Only 20-30% maintained growth | 35% |
Upbit IPO Case in 2025
| Tokens | Release Date | Initial increase | 30-day performance | Remark |
|---|---|---|---|---|
| IN | 2025.10.10 | +121% | +85% | AI DeFi projects, outstanding performance |
| API3 | 2025.8.21 | +100% | -40% | Oracle Network, Typical Callback |
| DRIFT | 2024.11.8 | +90% | +20% | Solana DEX, fundamentals support |
BIO Protocol Technical Analysis (Current Status)
Short-term technical analysis
| Timeframe | trend | RSI | Key Location | Signal |
|---|---|---|---|---|
| 1 hour | Bullish | 89.1 | $0.1022 resistance | 🟢 Strong rise, overbought risk |
| 4 hours | Bullish | 80.3 | $0.0965 resistance | 🟢 Momentum builds, ADX34 confirms strength |
| Daily Line | neutral | 49.3 | $0.1101 middle track | 🟡 Consolidation, price is between EMAs |
Key price levels and risks
- Support level : $0.105 (strong support, cumulative long liquidation $270k)
- Resistance : $0.112 (medium resistance, daily EMA26)
- Target : $0.136 (SMA50, strong resistance)
DeSci sector rebound potential assessment
Sector Catalysts
- Funding : Sei Foundation $65M DeSci Special Fund
- Regulatory Progress : South Korea's new president, Lee Jae-myung, extends tax payments to 2027, and an ETF pilot program launches.
- Technology Convergence : AI-DeSci Cross-Narrative, the Rise of Agent Science
- Ecosystem Development : Platforms like Molecule Promote IP Tokenization
Rebound probability analysis
| factor | Weight | score | Influence |
|---|---|---|---|
| Fundamentals | 30% | 7/10 | DeSci adoption accelerating, but in early stages |
| Technical aspects | 40% | 6/10 | Overall downtrend, but forming a bottom |
| Emotional side | 30% | 8/10 | KOL support and high narrative popularity |
Comprehensive judgment : medium rebound probability ( 60% ), target increase of 20-50%
Conclusions and Recommendations
While BIO didn't receive support from Upbit in January, the DeSci sector did perform strongly during that period. BIO, officially listed on Upbit on October 20th, saw a 40%+ surge in its price in a short period, a typical example of the "Upbit effect."
Investment advice :
- Short-term : Focus on a breakout of $0.112, target $0.136
- Mid-term : Waiting for value investment opportunities after a 50% correction
- Long-term : The DeSci sector benefits from the AI integration trend and has medium- to long-term investment value.
Risk Warning : The Upbit listing effect is highly short-term, with 89% of projects eventually experiencing price corrections. It is recommended to build positions in batches and maintain strict stop-loss orders.