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Paul Kohlhaas bio/acc
7,998 Twitter followers
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dreaming of a liquid singularity / founder @bio_xyz @molecule_dao pioneering @vita_dao @psy_dao / alum @linumlabs @Consensys @AfrikaBurn
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Paul Kohlhaas bio/acc
01-27
As the cost of computational science (modeling, simulation, discovery, publishing) trends toward zero thanks to AI, and as research outputs become increasingly modular, agentic, and composable, we can expect a Cambrian explosion of scientific IP to emerge organically. Yet real-world wet lab work remains capital-intensive. Agentic AI will speed up discovery by automating hypothesis testing, optimizing experiments + iterating protocols at unprecedented scale. This empowers a new science “idea guy” to bootstrap breakthroughs without massive upfront teams. That said, how will these outputs find funding? Every medium for new scientific IP has trended toward lower barriers: arXiv preprints, open-source repos, citizen science notebooks, short-form research tweets/threads… leading naturally to onchain tokenized assets (decentralized IP, agent-minted research DAOs, tokenized datasets/protocols) as the endgame Onchain science assets are low-cost to launch, global from day one, with programmable scarcity + provenance sans gatekeepers. Mints serve as a capital formation mechanism to crowdfund validation, wet-lab scaling, or replication. This will become the fastest, lowest-overhead way to bootstrap internet-native science @Molecule_sci tokenisation frameworks + @BioProtocol scientific AI will turbocharge this flywheel
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Paul Kohlhaas bio/acc
01-21
bio/acc playbook 1. DECENTRALIZE BIOPOWER Leverage decentralized networks for secure data storage, transactions, and crowdfunding to form global collectives that fund, coordinate, and monetize indie scientific research—bypassing legacy gatekeepers. Forge network states with fresh regs for safe, open clinical trials. 2. ENGINEER ETHICAL EVOLUTION Embed biosafety and accountability via smart contracts: immutable ledgers for privacy-preserving data with selective sharing. Communities flag pathogenic genes and enforce safeguards. Automate failsafes and governance through encryption, onchain voting, and consensus—fueling innovation under transparent, crowd-ruled standards. 3. ALIGN WITH ECOLOGICAL BLUEPRINTS Fuse biotech with ravaged ecosystems we've exploited to the edge. Adopt biomimicry: mimic nature's designs, processes, and systems. Open-source intelligent life forms that devour plastic, scrub CO2, and boost plant growth. 4. HACK HEALTH, CLAIM MIND-BODY LIBERTY Declare every sentient being's unalienable right to mod their minds and bodies—tweaking neurochemistry and cognition on their terms. Roll out open tools for safe self-experiments with nootropics and psychedelics: from DIY brain-computer interfaces to decentralized patient data hubs. Democratize longevity to counter population crashes. 5. OPEN-SOURCE SCIENTIFIC AI, SPREAD THE WEALTH Create a global commons for genomes, drug blueprints, and protocols via decentralized IP models powered by zero-knowledge proofs—ensuring equitable sharing of collective smarts, not elite hoarding. Log digital and physical science on distributed file systems. Life's code is public domain, not a vaulted secret. 6. ACCELERATE SUPPLY CHAINS Build direct-to-consumer pipelines to slash costs and timelines. Link global biomanufacturing into open markets for fresh innovations, generics, and treatments. 3D-print molecules on-demand, locally.
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