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<h3>Fireline Report</h3>
<p>BIO received spot support from Upbit, with KRW, BTC, and USDT markets launched simultaneously. It rose by nearly 27% within 15 minutes, with a significant influx of short-term funds.</p>
<h3>Trading Guide</h3>
<p>Driven by events, pay attention to the 0.135 USDT line. If it retreats and fails, the short-term heat will cool down. The linkage of sectors requires observing the DeSci capital flow.</p>
<p style="margin-top: 20px; text-align: left; opacity: 0.4; padding: 0 42px"><small>Updated at 10-21 07:21</small><br><small>AI-generated summary, not investment advice</small></p></div>

<h1>Analysis of the BIO Protocol Upbit Listing: Clarification of Timeline and DeSci Sector Outlook</h1><h2> Key findings</h2><p> <strong>Important clarification</strong> : The BIO protocol did not receive spot trading support on Upbit in January 2025. Research indicates that BIO&#39;s actual Upbit listing date was <strong>October 20, 2025</strong> , supporting KRW, BTC, and USDT trading pairs. In January 2025, BIO was only listed on exchanges such as Binance, Bitget, and Gate.io.</p><h2> DeSci sector performance analysis in January 2025</h2><h3> Overall trend of the sector</h3><p> In January 2025, the DeSci sector did show <strong>a strong bull market trend</strong> , with the following key indicators:</p><table><thead><tr><th> index</th><th> Performance</th><th> Driving factors</th></tr></thead><tbody><tr><td> Average increase</td><td> <strong>+11.55%</strong></td><td> New project listing boom</td></tr><tr><td> Sector market capitalization</td><td> ~ <strong>$900M</strong> (January 21st)</td><td> BIO and other major projects join</td></tr><tr><td> Market sentiment</td><td> Highly bullish</td><td> Endorsement by KOLs such as Vitalik</td></tr><tr><td> Number of new projects</td><td> 30+</td><td> Capital inflow and ecological expansion</td></tr></tbody></table><h3> Performance of major DeSci projects in January</h3><table><thead><tr><th> project</th><th> Market capitalization</th><th> January performance</th><th> Key Events</th></tr></thead><tbody><tr><td> <strong>BIO Protocol</strong></td><td> $324M</td><td> ATH $0.92 → $0.25 (-73%)</td><td> Binance listing on January 3</td></tr><tr><td> <strong>OriginTrail (TRAC)</strong></td><td> $350M+</td><td> Estimated +5-15%</td><td> Leader in Data Integrity</td></tr><tr><td> <strong>VitaDAO (VITA)</strong></td><td> ~$50M</td><td> Rising in tandem with the sector</td><td> Pioneer in longevity research</td></tr><tr><td> <strong>ResearchCoin (RSC)</strong></td><td> Peak $200M</td><td> ATH $1.51→$0.61 (-60%)</td><td> Record high on January 5</td></tr></tbody></table><h2> Historical Analysis of Upbit&#39;s Listing Effect</h2><h3> Typical manifestation patterns</h3><p> Based on historical data from 2024-2025, Upbit listings generally follow the following pattern:</p><table><thead><tr><th> stage</th><th> Timeframe</th><th> Price performance</th><th> Success rate</th></tr></thead><tbody><tr><td> <strong>Initial outbreak</strong></td><td> Listing day</td><td> <strong>+50-150%</strong></td><td> 70-80%</td></tr><tr><td> <strong>Peak hold</strong></td><td> 1-3 days</td><td> Volatility Consolidation</td><td> 37%</td></tr><tr><td> <strong>Callback phase</strong></td><td> 1-4 weeks</td><td> <strong>-50-70%</strong></td><td> 89%</td></tr><tr><td> <strong>Long-term performance</strong></td><td> 3-6 months</td><td> Only 20-30% maintained growth</td><td> 35%</td></tr></tbody></table><h3> Upbit IPO Case in 2025</h3><table><thead><tr><th> Tokens</th><th> Release Date</th><th> Initial increase</th><th> 30-day performance</th><th> Remark</th></tr></thead><tbody><tr><td> <strong>IN</strong></td><td> 2025.10.10</td><td> +121%</td><td> +85%</td><td> AI DeFi projects, outstanding performance</td></tr><tr><td> <strong>API3</strong></td><td> 2025.8.21</td><td> +100%</td><td> -40%</td><td> Oracle Network, Typical Callback</td></tr><tr><td> <strong>DRIFT</strong></td><td> 2024.11.8</td><td> +90%</td><td> +20%</td><td> Solana DEX, fundamentals support</td></tr></tbody></table><h2> BIO Protocol Technical Analysis (Current Status)</h2><h3> Short-term technical analysis </h3><p><reference tool_id="call_86213567" category="heatmap" project="BIO" description="BIO OI USD and 24h change percent by exchange at 2025-10-20 07:29 UTC"/></p><table><thead><tr><th> Timeframe</th><th> trend</th><th> RSI</th><th> Key Location</th><th> Signal</th></tr></thead><tbody><tr><td> 1 hour</td><td> Bullish</td><td> 89.1</td><td> $0.1022 resistance</td><td> 🟢 Strong rise, overbought risk</td></tr><tr><td> 4 hours</td><td> Bullish</td><td> 80.3</td><td> $0.0965 resistance</td><td> 🟢 Momentum builds, ADX34 confirms strength</td></tr><tr><td> Daily Line</td><td> neutral</td><td> 49.3</td><td> $0.1101 middle track</td><td> 🟡 Consolidation, price is between EMAs</td></tr></tbody></table><h3> Key price levels and risks </h3><p><reference tool_id="call_88540162" category="mix_bar_line_liquidation" project="BIO" description="BIO liquidation risk map by price level and exchange (1d period) at 2025-10-20 07:29 UTC"/></p><ul><li> <strong>Support level</strong> : $0.105 (strong support, cumulative long liquidation $270k)</li><li> <strong>Resistance</strong> : $0.112 (medium resistance, daily EMA26)</li><li> <strong>Target</strong> : $0.136 (SMA50, strong resistance)</li></ul><h2> DeSci sector rebound potential assessment</h2><h3> Sector Catalysts</h3><ol><li> <strong>Funding</strong> : Sei Foundation $65M DeSci Special Fund</li><li> <strong>Regulatory Progress</strong> : South Korea&#39;s new president, Lee Jae-myung, extends tax payments to 2027, and an ETF pilot program launches.</li><li> <strong>Technology Convergence</strong> : AI-DeSci Cross-Narrative, the Rise of Agent Science</li><li> <strong>Ecosystem Development</strong> : Platforms like Molecule Promote IP Tokenization</li></ol><h3> Rebound probability analysis</h3><table><thead><tr><th> factor</th><th> Weight</th><th> score</th><th> Influence</th></tr></thead><tbody><tr><td> <strong>Fundamentals</strong></td><td> 30%</td><td> 7/10</td><td> DeSci adoption accelerating, but in early stages</td></tr><tr><td> <strong>Technical aspects</strong></td><td> 40%</td><td> 6/10</td><td> Overall downtrend, but forming a bottom</td></tr><tr><td> <strong>Emotional side</strong></td><td> 30%</td><td> 8/10</td><td> KOL support and high narrative popularity</td></tr></tbody></table><p> <strong>Comprehensive judgment</strong> : medium rebound probability ( <strong>60%</strong> ), target increase of 20-50%</p><h2> Conclusions and Recommendations</h2><p> While BIO didn&#39;t receive support from Upbit in January, the DeSci sector did perform strongly during that period. BIO, officially listed on Upbit on October 20th, saw a 40%+ surge in its price in a short period, a typical example of the &quot;Upbit effect.&quot;</p><p> <strong>Investment advice</strong> :</p><ul><li> <strong>Short-term</strong> : Focus on a breakout of $0.112, target $0.136</li><li> <strong>Mid-term</strong> : Waiting for value investment opportunities after a 50% correction</li><li> <strong>Long-term</strong> : The DeSci sector benefits from the AI integration trend and has medium- to long-term investment value.</li></ul><p> <strong>Risk Warning</strong> : The Upbit listing effect is highly short-term, with 89% of projects eventually experiencing price corrections. It is recommended to build positions in batches and maintain strict stop-loss orders.</p>
