Some good adds from the comments:
Polymarket was not the first prediction market (Augur)
Blur was not the first NFT exchange (OpenSea)
Metamask was not the first EVM wallet (Mist)
Phantom was not the first SOL wallet (Solflare)
Safe was not the first multisig (Parity)

Twitter

Angrybot launches Moonshot listing monitoring, the first bot that supports Moonshot listing signals.
Why monitor Moonshot listings? What wealth codes are there?
<Moonshot>, the hottest trading application recently, is called the "small Binance", the coins listed on it have a strong wealth effect. In fact, the community has already shouted that it may replace Binance in the future and become a new "listing" center, a new bull market engine.
Why?
<Moonshot> product is close to: <MEME> coin dedicated wallet + aggregated DEX liquidity...

"Little Binance on the chain", can listing a coin boost the market? Angrybot launches the first Moonshot coin listing monitoring on the entire network, easily catching 100x large MC memecoin

The Bitcoin Dominance index for the first time since 03/2021 has conquered the threshold of 59% in the context of a strong increase in BTC prices, while altcoins have not shown any signs of improvement.
Bitcoin Dominance surpassed the 59% mark, setting a new high in 3 years...

Bitcoin Dominance Surpasses 59%, Hits 3-Year High

Recently, @truth_terminal and $GOAT ignited the combination of AI and <MEME>. I have summarized the data of <MEME>s with a market capitalization of over $20 million on @CoinMarketCap, and found some interesting data.

This statistical survey covers a total of 127 <MEME>s, of which 8 exceed $1 billion. <Solana> has become the most popular chain for <MEME>s, with 38.6% deployed on <Solana>, <ETH>, ...