The synthetic opioid crisis continues to devastate communities across the United States, with fentanyl-related deaths contributing to tens of thousands of fatalities annually. As criminals increasingly turn to cryptocurrency to facilitate these deadly transactions, leading crypto exchanges are taking proactive measures to identify and disrupt these networks before they can cause further harm.
Coinbase, one of the world’s largest cryptocurrency exchanges, launched a comprehensive “sprint” targeting the crypto nexus of fentanyl trafficking as part of their proactive risk management strategy. This focused investigation, supported by Chainalysis intelligence, demonstrates how forward-thinking industry leaders can effectively disrupt criminal networks through strategic threat detection and coordinated law enforcement collaboration.
Coinbase’s strategic approach: Why “sprints” matter
Coinbase has pioneered the use of focused “sprints” as a cornerstone of their proactive risk management strategy. These intensive, time-bound investigations represent a departure from traditional reactive compliance approaches, allowing the exchange to systematically identify and eliminate threats before they can cause significant harm.
Coinbase conducts sprints for several strategic reasons:
- Single-focus investigations reduce intelligence gaps while broadening capabilities to detect fresh, unfamiliar criminal methodologies that might otherwise go unnoticed.
- Dedicated time on specific crime categories removes the pressure of business-as-usual operations, enabling meticulous study and analysis that would be impractical during routine operations.
- To uphold their reputation as one of the most trusted cryptocurrency exchanges, sprints provide opportunities to systematically cleanse the platform of undetected threats.
- Beyond promoting team cohesion and training newer investigators, sprints create opportunities to build stronger relationships with law enforcement agencies worldwide.
For this fentanyl-focused sprint, Coinbase established four key objectives:
- Disrupt and dismantle rogue chemists using cryptocurrency
- Develop practical solutions to improve detection rates and prevent platform exploitation
- Create sustainable frameworks for continued intelligence sharing between public and private sectors
- Systematically remove high-risk actors from their platform to protect users and maintain platform integrity
To support this ambitious initiative, Coinbase leveraged Chainalysis’s comprehensive blockchain intelligence capabilities, using our data and analytical tools to identify criminal networks and trace the flow of illicit funds.
The methodology: A four-phase intelligence operation
To execute the sprint, Coinbase deployed a comprehensive four-phase approach involving data collection, target identification, case construction, and escalation.
Phase 1: Data collection and intelligence aggregation
Using Chainalysis Data Solutions, our Global Services team ran a query using our on-chain datasets to identify all direct and indirect exposure from Coinbase to chemical manufacturers and related entities. This comprehensive mapping revealed the full scope of potentially illicit activity touching Coinbase’s platform.
The investigation also leveraged our Signals dataset to triage intelligence and rank entities according to risk levels. Each user received a risk score between 1 and 100, with entities categorized across a priority threat spectrum: critical, very high, high, moderate, or routine. This systematic approach allowed Coinbase to focus resources on the highest-priority threats.
Phases 2 – 4: Target identification, case construction, and escalation
Following data collection, the teams moved through systematic target identification and case construction phases, building comprehensive intelligence packages that could support both platform risk management and law enforcement action.
The results: Substantial criminal network exposure
The sprint yielded significant intelligence that revealed the scope and sophistication of fentanyl-related cryptocurrency activity:
- Broad scope of investigation: Thousands of deposit addresses and user accounts were analyzed.
- High transaction volume: The team tracked and mapped 17,000+ cryptocurrency transactions, illuminating key patterns in how funds were moved.
- Actionable insights: The intelligence generated provided a detailed view into the digital infrastructure underpinning illicit fentanyl distribution.
- Geographic distribution: While the majority of users were located in the United States, the investigation also identified criminal actors in France, the United Kingdom, Australia, Canada, and Germany — highlighting the truly transnational nature of these networks. As a result of the sprint, a criminal actor has also been charged by the Financial and Cyber Crime Group (FCCG) of the Queensland Police in Australia.
- Cryptocurrency preferences: Bitcoin dominated the transaction landscape, accounting for 97% of all observed transactions. Despite the growing adoption of stablecoins in other illicit activities, fentanyl traffickers demonstrated a strong preference for Bitcoin, likely due to its established liquidity and market acceptance. This resistance to change reflects the conservative nature of established criminal enterprises when their current methods remain effective.
Case study: Following the money trail
Using Chainalysis Reactor, investigators mapped the complex flow of funds for one high-priority subject, revealing sophisticated money laundering patterns that connected darknet markets to legitimate cryptocurrency exchanges.

The analysis showed more than $10 million in total transaction volume between the subject’s Coinbase account and a network of criminal counterparties, with nearly $4 million in receiving exposure. The investigation also revealed a pattern where hundreds of thousands of dollars flowed from multiple darknet markets into intermediary wallets before ultimately reaching the subject’s deposit address at Coinbase.
This transactional pattern provided critical insights: the subject was operating either as a vendor or supplier to vendors on darknet markets. Beyond direct marketplace activity, the investigation also identified indirect exposure to entities selling synthetic chemicals used in fentanyl production, including connections to OFAC-sanctioned entities.
Taking action: From intelligence to impact
Armed with comprehensive intelligence, Coinbase took decisive action to manage these risks through a two-pronged approach:
Platform protection: Coinbase’s compliance team used the intelligence to remove high-risk users from their platform, preventing further illicit transactions and protecting the integrity of their services.
Law enforcement collaboration: For the most severe cases, Coinbase compiled detailed reports for proactive law enforcement referrals. The sprint resulted in 41 intelligence packages distributed across 12 countries, including the United States, Germany, United Kingdom, Spain, Hungary, Netherlands, Belgium, Czech Republic, and Australia, as well as Europol and Interpol. These investigations remain ongoing.
The broader impact: Strengthening the ecosystem
This successful sprint demonstrates several critical principles for combating cryptocurrency-enabled crime:
Proactive monitoring: Rather than waiting for external reports or regulatory action, proactive threat detection allows platforms to identify and disrupt criminal activity before it can cause further harm.
Advanced analytics: Sophisticated blockchain intelligence software like Chainalysis Reactor and Data Solutions, combined with extensive datasets like Signals enable investigators to see beyond individual transactions to understand entire criminal ecosystems and their interconnections.
Global collaboration: The transnational nature of fentanyl trafficking requires coordinated international responses, powered by shared intelligence and standardized analytical approaches.
Public-private partnership: The collaboration between Chainalysis, Coinbase, and law enforcement agencies worldwide exemplifies how industry cooperation can amplify the impact of individual enforcement actions.
Empowering organizations with Chainalysis Data Solutions
This investigation’s success was powered by Chainalysis Data Solutions (DS) alongside support from our Global Services and Global Intelligence teams whose expertise helped Coinbase extract maximum value from the data and accelerate progress toward their goals.
Chainalysis DS is designed to be the industry’s most customizable threat intelligence data platform, providing cryptocurrency businesses, financial institutions, and government agencies with the intelligence they need to combat financial crime.
It offers direct access to Chainalysis’s extensive cryptocurrency intelligence, enabling organizations to:
- Conduct advanced risk assessments: Access our complete dataset on cryptocurrency addresses, entities, and transaction patterns to make informed compliance decisions
- Build custom analytics: Integrate Chainalysis data directly into existing workflows and compliance systems for seamless risk management
- Scale investigation capabilities: Leverage our intelligence to identify connections and patterns that would be impossible to detect manually
- Stay ahead of emerging threats: Access continuously updated intelligence on new criminal methodologies and entity attributions
For organizations looking to replicate this type of proactive threat detection and intelligence-driven approach to cryptocurrency compliance, Data Solutions provides the foundational intelligence necessary to identify, investigate, and disrupt criminal activity at scale.
Building a Safer Financial Future Together
The fentanyl crisis demands innovative solutions that match the sophistication and adaptability of criminal networks. This sprint between Chainalysis and Coinbase demonstrates that, when industry leaders commit to proactive risk management, powered by advanced blockchain intelligence and supported by strong public-private partnerships, meaningful disruption of criminal activity becomes possible.
As we continue to develop new tools and methodologies to combat this threat, the lessons learned from this collaboration will inform broader efforts to protect communities from the devastating impact of synthetic opioids. The fight against fentanyl trafficking requires sustained commitment, international cooperation, and the continued evolution of our analytical capabilities.
At Chainalysis, we remain committed to empowering our partners across the cryptocurrency ecosystem and law enforcement community with the intelligence they need to disrupt these deadly networks and build a safer financial future for all.
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