Your body will give warning signs: 1. Erectile dysfunction: Beware of heart attack. Because the blood vessels in the penis are finer, warning signs can appear 3-5 years in advance. 2. Increased nighttime urination: Not just for the kidneys/prostate, but also indicating cardiovascular risk. 3. Shortness of breath while walking/climbing stairs: Not necessarily a lung problem, but could indicate cardiovascular risk. 4. Persistent low mood: Not necessarily depression, but could also be due to undetected underlying inflammation. 5. Increased waist circumference: Beware of insulin resistance.